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Ever had red, itchy welts suddenly show up on your skin? That could be hives. Dr. Sheila Bonilla explains what's happening on your skin and the treatments that can help bring relief. #
During a drug overdose, more APAP is converted by cytochrome P450 enzymes into NAPQI, leading to liver injury through mechanisms including oxidative stress, binding to macromolecules, mitochondrial dysfunction, and endoplasmic reticulum stress [13,14] (Figure 1)
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10.2147/JIR.S459449 42 LiuY.LiM.MeiC.CuiH.WangQ.LiD.et al (2022b)
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